Endocrine Abstracts

Objective(s): Last data showed advantages of TBS assessment of bone quality over BMD in patients with type 2 diabetes (T2D). We perform DXA in patients with T2D and calculated 10-year probability of fracture using FRAX® tool.Material and methods: A total of 252 (172 females) T2D patients aged 36 to 86 y.o (mean 61.0±8.8) were examined. BMD was performed in 124 patients (110 females) using DXA (Lunar Prodigy, USA). BMD adjusted for TB...

Background: In recent years, the role of vitamin D in improving the profile of inflammatory markers in order to prevent and treat diabetic neuropathy and microcirculation disorders has been actively studied.Aims: The research goal was to study the dynamics of inflammatory markers, clinical manifestations of diabetic peripheral neuropathy and laser Doppler flowmetry of skin microcirculation during treatment with various doses of cholecalciferol in patient...

Objective: Recent studies suggest that vitamin D deficiency could be a risk factor for metabolic abnormalities.The aim of this study was to assess the relationship between 25(OH)D level and metabolic syndrome components.Materials and methods: A total of 697 women from 30 to 55 y.o. were examined. Exclusion criteria were, clinically significant endocrine, renal, liver and GI diseases, regular insolation and intake of vitamin D and c...

Background: Recently, clinical evidence of thyroid dysfunction has been observed both in acute and post-COVID period. The aim of this study was to estimate the serum TSH level in hospitalized patients with moderate-to-severe COVID-19.Methods: It was a single-center study conducted by the Almazov National Medical Research Centre (Russian Federation). Patients hospitalized with detected SARS-CoV-2 infection by RT-PCR test and chest computed tomography (CT)...

Objective(s): Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphisms can be associated with atherogenic lipid profile. The results of recent studies in different populations are contradictory. The aim of study was to assess serum lipids in women with different vitamin D status carrying various VDR gene variants.Materials and methods: We examined 697 women aged 35 to 55 y.o. (mean 43.4±0.3). Anthropometric parameters (...